 FT | Al-Fayha  | 2 - 2 |  Al Kholood | |
 FT | Palermo  | 5 - 2 |  Mantova | |
 FT | Raków Częstochowa  | 1 - 2 |  Górnik Zabrze | |
 FT | Thisted FC  | 0 - 2 |  Sonderjyske | |
FT | NEOM  | 3 - 0 |  Al Khaleej Saihat | |
 FT | Mjällby  | 0 - 2 |  Djurgardens IF | |
 FT | FC København  | 2 - 0 |  Nordsjælland | |
FT | Al Diriyah  | 0 - 2 |  Al-Qadisiyah FC | |
FT | Lech Poznań  | 2 - 1 |  Jagiellonia Białystok | |
 FT | FC Basel 1893  | 1 - 2 |  Sion | |
FT | Lugano  | 1 - 0 |  Servette FC | |
 FT | Gent  | 1 - 0 |  OH Leuven | |
FT | Anderlecht  | 1 - 0 |  Kortrijk | |
 FT | Slask Wroclaw  | 2 - 1 |  Pogon Szczecin | |
 FT | Toulouse  | 0 - 1 |  LOSC Lille | |
 FT | Hibernian  | 1 - 3 |  Hearts | |
 | Gremio  | vs |  Internacional | |
 | Arema FC  | vs |  Adhyaksa | |
 | Trường Tươi Đồng Nai  | vs |  Thể Công-Viettel | |
 | Jabal Al Mukaber  | vs |  Shabab Al Khaleel | |
| Bali United  | vs |  PSS Sleman | |
| Abha  | vs |  Al-Ettifaq | |
 | SV Kapfenberg  | vs |  WSPG Wels | |
| SCR Altach  | vs |  Bischofshofen |